Result Untitled Document Protein SSourceMus musculus (house mouse) Taxonomy Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.KeywordsBlood coagulation; Calcium; Cleavage on pair of basic residues; Disulfide bond; EGF-like domain; Gamma-carboxyglutamic acid; Glycoprotein; Hydroxylation; Repeat; Secreted; Signal; Zymogen.DetailsFunction: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. Post-translational modification: The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains (By similarity). Similarity: Contains 4 EGF-like domains. Contains 1 Gla (gamma-carboxy-glutamate) domain. Contains 2 laminin G-like domains. Subcellular location: Secreted. Tissue specificity: Plasma. Sequence length: 675 AA. SequenceMRVLSARFRVLLACLALVIPVSETNFLSKERASQVLVRKRRANTLFEETMKGNLERECIEELCNKEEAREVFENNPETDYFYPKYLGCLGAFRVGSFHAARQSANAYPDLRSCVKAISDQCDPIPCNEDGYLACQDGQAAFTCFCKPGWQGDRCQYDVNECKDPSNVNGGCSQICDNTPGSYHCSCKRGFAMLPNKKDCKDLDECALKPSVCGTAVCKNIPGDFECECPDGYRYDPSSKSCKDVDECSENMCAQLCVNFPGGYSCYCDGKKGFKLAQDQKSCEGIPVCLSLDLDKNYELLYLAEQFAGVVLYLKFRLPDITRFSAEFDFRTYDSEGIILYAESLDHSNWLLIALRDGKIEVQFKNEFSTQITTGGNVINNGIWNMVSVEELDDSVSIKIAKEAVMNINKLGSLFKPTDGFLDTKIYFAGLPRKVESALIKPINPRLDGCIRGWNLMKQGALGAKEIIEGKQNKHCFLNVEKGSYYPGSGIAQFSIDYNNVTNAEGWQMNVTLNIRPSTGTGVMLALVSGGTVPFALSLVDSRSGTSQDIVVFVENSVVARLEAVSLCSDQQSQLKCNVNRNGLELWTPLRKDVIYSKDLQRQLAVLDKAMKRTVATYLGGIPDISFSATPVNAFYSGCMEVNINGVQLDLDEAISKHKDIRAHSCPSVRKIQKNFAccession NumberQ08761 PubMed ID8148380, 8029814 CEX DBMM_PROS1CTD DB19128eggNOG DBroNOG12747Ensembl DBENSMUST00000023629CATHG3DSA:4.10.740.10, G3DSA:2.60.120.200GeneID DB19128GermOnline DBENSMUSG00000022912GO DB0005576, 0005509, 0007596HOGENOM DBHBG444981InterPro DBIPR017857, IPR002383, IPR008985, IPR013320, IPR006210, IPR013032, IPR000152, IPR000742, IPR001881, IPR013091, IPR018097, IPR000294, IPR001791, IPR012679, IPR012680IPI DBIPI00124374KEGGmmu:19128NCBIZ25469, CAA80961, L27439, AAA40006, NP_035303OMANMVSVEEOMIM105200, 134820, 202400, 134830, 202400, 134850, 202400, 176930, 601367, 134390, 188055, 227400, 600880, 601367, 612309, 227500, 134500, 306700, 300746, 306900, 227600, 176860, 188050, 612283, 612304, 176880, 612336OrthoDBEOG93BQ7JPfamPF07645, PF00594, PF00054, PF02210PROSITE DBPS00010, PS00022, PS01186, PS50026, PS01187, PS00011, PS50998, PS50025SMART DBSM00181, SM00179, SM00069, SM00282UCSCuc007zpx.1UniGeneMm.127156
Result
Protein S
Function: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. Post-translational modification: The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains (By similarity). Similarity: Contains 4 EGF-like domains. Contains 1 Gla (gamma-carboxy-glutamate) domain. Contains 2 laminin G-like domains. Subcellular location: Secreted. Tissue specificity: Plasma. Sequence length: 675 AA.
MRVLSARFRVLLACLALVIPVSETNFLSKERASQVLVRKRRANTLFEETMKGNLERECIEELCNKEEAREVFENNPETDYFYPKYLGCLGAFRVGSFHAARQSANAYPDLRSCVKAISDQCDPIPCNEDGYLACQDGQAAFTCFCKPGWQGDRCQYDVNECKDPSNVNGGCSQICDNTPGSYHCSCKRGFAMLPNKKDCKDLDECALKPSVCGTAVCKNIPGDFECECPDGYRYDPSSKSCKDVDECSENMCAQLCVNFPGGYSCYCDGKKGFKLAQDQKSCEGIPVCLSLDLDKNYELLYLAEQFAGVVLYLKFRLPDITRFSAEFDFRTYDSEGIILYAESLDHSNWLLIALRDGKIEVQFKNEFSTQITTGGNVINNGIWNMVSVEELDDSVSIKIAKEAVMNINKLGSLFKPTDGFLDTKIYFAGLPRKVESALIKPINPRLDGCIRGWNLMKQGALGAKEIIEGKQNKHCFLNVEKGSYYPGSGIAQFSIDYNNVTNAEGWQMNVTLNIRPSTGTGVMLALVSGGTVPFALSLVDSRSGTSQDIVVFVENSVVARLEAVSLCSDQQSQLKCNVNRNGLELWTPLRKDVIYSKDLQRQLAVLDKAMKRTVATYLGGIPDISFSATPVNAFYSGCMEVNINGVQLDLDEAISKHKDIRAHSCPSVRKIQKNF
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