Result

  Coagulation factor III

Source	Rattus norvegicus (Norway rat)
Taxonomy	Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
Keywords	Blood coagulation; Disulfide bond; Glycoprotein; Lipoprotein; Membrane; Palmitate; Signal; Transmembrane.
Details Function: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. Similarity: Belongs to the tissue factor family. Subcellular location: Membrane; Single-pass type I membrane protein. Sequence length: 295 AA.
Sequence MAIPMRPRLLAALAPTFLGFLLLQVAVGAGTPPGKAFNLTWISTDFKTILEWQPKPTNYT YTVQISDRSRNWKYKCTGTTDTECDLTDEIVKDVNWTYEARVLSVPWRNSTHGKETLFGT HGEEPPFTNARKFLPYRDTKIGQPVIQKYEQGGTKLKVTVKDSFTLVRKNGTFLTLRQVF GNDLGYILTYRKDSSTGRKTNTTHTNEFLIDVEKGVSYCFFAQAVIFSRKTNHKSPESIT KCTEQWKSVLGETLIIVGAVVFLVTVFIILLTISLCKRRKNRAGQKRKNTPSRLA
Accession Number	P42533
PubMed ID	8950776
eggNOG DB	roNOG06715
Ensembl DB	ENSRNOT00000015836
CATH	G3DSA:2.60.40.30
GermOnline DB	ENSRNOG00000011800
GO DB	0016021, 0002020, 0007596
InterPro DB	IPR008957, IPR015373, IPR016354, IPR001187
IPI DB	IPI00197592
NCBI	U07619, AAA16966
OMIM	105200, 134820, 202400, 134830, 202400, 134850, 202400, 176930, 601367, 134390
Pfam	PF09294, PF01108
PROSITE DB	PS00621
UCSC	NM_013057
UniGene	Rn.9980