Result Untitled Document Coagulation factor XIII B chainSourceBos taurus (cattle) Taxonomy Bos taurus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.DetailsFunction: The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. Similarity: Contains 10 Sushi (CCP/SCR) domains. Subunit structure: Tetramer of two A chains and two B chains. Tissue specificity: Predominantly expressed in liver and kidney. Sequence length: 661 AA. SequenceMRSKSLALIIILIISGELHAEEKPCGFPSVENGRIAQYYYIFESYYFPMSINQNLAFSCLVGYTTATGKREARTTCTAAGWSPEPRCFKKCPKPDLKNGYIFDSKLSYKIQENMRYRCTSGYKTMAGQDEEVVQCLADGWSPQPTCSKEHETCLAPELHHGNYFTTQKTFKVKERVRYECASGYHTASGKSTEEAECHPYGWALTPQCTKLKCSSLRVIENGYFHPVKQTYEEGDVVQFFCHKNYYLSGSDLIQCYNFGWYPESPVCEGRRNRCPPLPLPLNSNLQTYSTTYRHGETVRIECALNFAMQGAEEIRCENGKWTEPPRCVEDKQRMTCEAPPSVEHGTTTPSSEVYHSGDKVAYVCERGYHLRGPGEITCNRGRWTLPPECVENTENCNPPPDVINGAIIGELLASYPTGSSVEYRCNEYYLLRGAKISHCEQGRWSSPPVCLEPCTVNVGDMRRNHVELKWNYEGKILHGDLIDFVCKQGYELSPSTPPSELSVQCDRGEVKYPSCVRKESKRMCASPPAIKNGVIKSSTLSTYENGSSVEYICFKHHFLQGARESYCLEGVWTTPPSCLEPCTLSFDTMENNNLLLKWNFDNRPYIFHGEYVEFLCKGDTYIAGFPDPVSESRVQCDRGQLNYPRCVQRERMLSYQEPLRTAccession NumberQ2TBQ1 InterPro DBIPR000436KEGGbta:511483NCBIBC109839, AAI09840OMIM105200, 134820, 202400, 134830, 202400, 134850, 202400, 176930, 601367, 134390, 188055, 227400, 600880, 601367, 612309, 227500, 134500, 306700, 300746, 306900, 227600, 176860, 188050, 612283, 612304, 176880, 612336, 264900, 612416, 234000, 610618, 610619, 229000, 612423, 107300, 188050, 134570, 134580PfamPF00084PROSITE DBPS50923SMART DBSM00032
Result
Coagulation factor XIII B chain
Function: The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. Similarity: Contains 10 Sushi (CCP/SCR) domains. Subunit structure: Tetramer of two A chains and two B chains. Tissue specificity: Predominantly expressed in liver and kidney. Sequence length: 661 AA.
MRSKSLALIIILIISGELHAEEKPCGFPSVENGRIAQYYYIFESYYFPMSINQNLAFSCLVGYTTATGKREARTTCTAAGWSPEPRCFKKCPKPDLKNGYIFDSKLSYKIQENMRYRCTSGYKTMAGQDEEVVQCLADGWSPQPTCSKEHETCLAPELHHGNYFTTQKTFKVKERVRYECASGYHTASGKSTEEAECHPYGWALTPQCTKLKCSSLRVIENGYFHPVKQTYEEGDVVQFFCHKNYYLSGSDLIQCYNFGWYPESPVCEGRRNRCPPLPLPLNSNLQTYSTTYRHGETVRIECALNFAMQGAEEIRCENGKWTEPPRCVEDKQRMTCEAPPSVEHGTTTPSSEVYHSGDKVAYVCERGYHLRGPGEITCNRGRWTLPPECVENTENCNPPPDVINGAIIGELLASYPTGSSVEYRCNEYYLLRGAKISHCEQGRWSSPPVCLEPCTVNVGDMRRNHVELKWNYEGKILHGDLIDFVCKQGYELSPSTPPSELSVQCDRGEVKYPSCVRKESKRMCASPPAIKNGVIKSSTLSTYENGSSVEYICFKHHFLQGARESYCLEGVWTTPPSCLEPCTLSFDTMENNNLLLKWNFDNRPYIFHGEYVEFLCKGDTYIAGFPDPVSESRVQCDRGQLNYPRCVQRERMLSYQEPLRT
©Biomedical Informatics Centre, NIRRH, Mumbai