Result

  Coagulation factor VIII

Source	Pan troglodytes (chimpanzee)
Taxonomy	Pan troglodytes Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan.
Details Function: Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa (By similarity). Similarity: Belongs to the multicopper oxidase family. Contains 3 F5/8 type A domains. Contains 2 F5/8 type C domains. Contains 6 plastocyanin-like domains. Subcellular location: Secreted, extracellular space (By similarity). Subunit structure: Interacts with vWF. vWF binding is essential for the stabilization of F8 in circulation (By similarity). Sequence length: 155 AA.
Sequence PLLVCHTNTLNPAHGRQVTVQEFALFFTIFDETKSWYFTENMERNCRAPCNIQMEDPTFK ENYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSGHVFTVRKKEEYKM ALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHA
Accession Number	Q2VF44
PubMed ID	16020776
GO DB	0005507, 0016491
InterPro DB	IPR011706, IPR008972
NCBI	DQ173563, ABB58722
OMIM	105200, 134820, 202400, 134830, 202400, 134850, 202400, 176930, 601367, 134390, 188055, 227400, 600880, 601367, 612309, 227500, 134500, 306700
Pfam	PF07731