Result

  Coagulation factor III

Source	Cavia porcellus (domestic guinea pig)
Taxonomy	Cavia porcellus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricognathi; Caviidae; Cavia.
Keywords	Blood coagulation; Disulfide bond; Glycoprotein; Lipoprotein; Membrane; Palmitate; Signal; Transmembrane.
Details Function: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. Similarity: Belongs to the tissue factor family. Subcellular location: Membrane; Single-pass type I membrane protein. Sequence length: 289 AA.
Sequence MTTPAWPRLPHPEIAVVPTLLLGWVLVQVAGAEGIPVKPYNLTWKSTNFKTILEWEPKPI NNVYTVQISTALEDWKSICFSITATECDLTSEMAPNVQQTYLARVISLLPNSTGFLEDAV YSNSPEFTPYQETNLGQPKIESFKLVGTKLNVTVRDTQTLARSNGTFLSLRDIFGKNLQY MLYYWRSSTTGKKTAMTNTNEFLIDVDKGQDYCFFVQAVIPSRKDNKKSPESITVCTRLE KGKFREMSFIVVPVILVIIVVIALFLLVCKCRKAKARQSGKEGSPLNIA
Accession Number	Q9JLU8
PubMed ID	10744153
eggNOG DB	roNOG06715
Ensembl DB	ENSCPOT00000002119
CATH	G3DSA:2.60.40.30
GO DB	0016021, 0007596
InterPro DB	IPR008957, IPR015373, IPR016354, IPR001187
NCBI	AF131949, AAF36523
OMIM	105200, 134820, 202400, 134830, 202400, 134850, 202400, 176930, 601367, 134390
Pfam	PF09294, PF01108
PROSITE DB	PS00621