Result

  Coagulation factor III

Source	Homo sapiens (human)
Taxonomy	Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Keywords	3D-structure; Blood coagulation; Complete proteome; Disulfide bond; Glycoprotein; Lipoprotein; Membrane; Palmitate; Polymorphism; Signal; Transmembrane.
Details Function: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. Similarity: Belongs to the tissue factor family. Subcellular location: Membrane; Single-pass type I membrane protein. Sequence length: 295 AA.
Sequence METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK PVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGS AGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFG KDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVE CMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS
Accession Number	P13726
PubMed ID	2823875, 3297348, 3037536, 3424286, 2719931, 16710414, 15489334, 3166978, 8086403, 8609606, 8598903, 9925787
CEX DB	HS_F3
CTD DB	2152
DIP DB	DIP-6136N
eggNOG DB	prNOG20681
Ensembl DB	ENST00000334047
CATH	G3DSA:2.60.40.30
Genecard DB	GC01M094706
GeneID DB	2152
GermOnline DB	ENSG00000117525
GO DB	0031012, 0005615, 0016021, 0031233, 0043498, 0005543, 0002020, 0002543, 0006919, 0002541, 0006916, 0007598, 0045766, 0030335, 0001938, 0010641, 0050927, 0051897
HGNC DB	3541
HOGENOM DB	HBG445882
HPA DB	CAB009438
InterPro DB	IPR008957, IPR015373, IPR016354, IPR001187
H-InvDB	HIX0000795
IPI DB	IPI00010338
KEGG	hsa:2152
NCBI	M16553, AAA61151, J02931, AAA61150, M27436, AAA36734, J02846, AAA61152, BT019808, AAV38611, CR541792, CAG46591, AF540377, AAN01236, AL138758.7, BC011029, AAH11029, NP_001984
NMPDR	fig|9606.3.peg.1526
OMA	NTNEFLI
OMIM	105200, 134820, 202400, 134830, 202400, 134850, 202400, 176930, 601367, 134390
OrthoDB	EOG9TXFBN
PDB	1AHW_C, 1AHW_F, 1BOY_A, 1DAN_T, 1DAN_U, 1FAK_T, 1J9C_T, 1JPS_T, 1NL8_T, 1O5D_T, 1TFH_A, 1TFH_B, 1UJ3_C, 1W0Y_T, 1W2K_T, 1WQV_T, 1WSS_T, 1WTG_T, 1WUN_T, 1WV7_T, 1Z6J_T, 2A2Q_T, 2AEI_T, 2AER_T, 2B7D_T, 2B8O_T, 2C4F_T, 2C4F_U, 2CEF_A, 2CEH_A, 2CEZ_A, 2CFJ_A, 2EC9_T, 2EC9_U, 2F9B_T, 2FIR_T, 2FLB_T, 2FLR_T, 2HFT_A, 2PUQ_T, 2ZP0_T, 2ZWL_T, 2ZZU_T, 3ELA_T
Pfam	PF09294, PF01108
PharmaGKB	PA24407
PROSITE DB	PS00621
UCSC	uc001dqr.1
UniGene	Hs.62192