Result Untitled Document Coagulation factor IIISourceOryctolagus cuniculus (rabbit) Taxonomy Oryctolagus cuniculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.Keywords3D-structure; Blood coagulation; Disulfide bond; Glycoprotein; Lipoprotein; Membrane; Palmitate; Repeat; Signal; Transmembrane.DetailsFunction: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.Similarity: Belongs to the tissue factor family. Contains 2 fibronectin type-III domains. Subcellular location: Membrane; Single-pass type I membrane protein. Tissue specificity: Brain, heart. Sequence length: 292 AA. SequenceMAPPTRLQVPRPGTAVPYTVLLGWLLAQVARAADTTGRAYNLTWKSTNFKTILEWEPKSIDHVYTVQISTRLENWKSKCFLTAETECDLTDEVVKDVGQTYMARVLSYPARNGNTTGFPEEPPFRNSPEFTPYLDTNLGQPTIQSFEQVGTKLNVTVQDARTLVRRNGTFLSLRAVFGKDLNYTLYYWRASSTGKKTATTNTNEFLIDVDKGENYCFSVQAVIPSRKRKQRSPESLTECTSREQGRAREMFFIIGAVVVVALLIIVLSVTVYKCRKARAGPSGKESSPLNIAAccession NumberP24055 PubMed ID1840552, 1746002, 9605315 eggNOG DBmaNOG15130CATHG3DSA:2.60.40.30GeneID DB100009127GO DB0016021, 0007596InterPro DBIPR008957, IPR003961, IPR015373, IPR016354, IPR001187NCBIM55390, AAA63469, X53521, CAA37597OMIM105200, 134820, 202400, 134830, 202400, 134850, 202400, 176930, 601367, 134390PfamPF09294, PF01108PROSITE DBPS50853, PS00621UniGeneOcu.2020
Result
Coagulation factor III
Function: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.Similarity: Belongs to the tissue factor family. Contains 2 fibronectin type-III domains. Subcellular location: Membrane; Single-pass type I membrane protein. Tissue specificity: Brain, heart. Sequence length: 292 AA.
MAPPTRLQVPRPGTAVPYTVLLGWLLAQVARAADTTGRAYNLTWKSTNFKTILEWEPKSIDHVYTVQISTRLENWKSKCFLTAETECDLTDEVVKDVGQTYMARVLSYPARNGNTTGFPEEPPFRNSPEFTPYLDTNLGQPTIQSFEQVGTKLNVTVQDARTLVRRNGTFLSLRAVFGKDLNYTLYYWRASSTGKKTATTNTNEFLIDVDKGENYCFSVQAVIPSRKRKQRSPESLTECTSREQGRAREMFFIIGAVVVVALLIIVLSVTVYKCRKARAGPSGKESSPLNIA
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