Result Untitled Document Protein SSourceMacaca mulatta (rhesus monkey) Taxonomy Macaca mulatta Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.KeywordsBlood coagulation; Calcium; Cleavage on pair of basic residues; Disulfide bond; EGF-like domain; Gamma-carboxyglutamic acid; Glycoprotein; Hydroxylation; Repeat; Secreted; Zymogen.DetailsFunction: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. Post-translational modification: The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains (By similarity). Similarity: Contains 4 EGF-like domains. Contains 1 Gla (gamma-carboxy-glutamate) domain. Contains 2 laminin G-like domains. Subcellular location: Secreted. Tissue specificity: Plasma. Sequence length: 649 AA. SequenceSKQQASQVLVRKRRANSMLEETKQGNLERECIEELCNKEEAREVFENDPETDYFYPKYLVCLRSFQSGLFTAARQSTDAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGERCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKSGFVMLSNKKDCKDVDECSLKPNMCGTAVCKNIPGDFECECPEGYRYNLKSKSCEDVDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEAVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSQGVILYAESIDHSAWLLIALRGGKIEVQLKNEHTSKITTGGDIINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAEFHIDYNNGSNAEGWHINVTLNIRPSTGTGVMLALVSSNNTVPFAVSLVDSTSEKSQDIVISVENTVIYRIQALSLCSYQRSHLEFRVNRNNLELLTPLKIETISQEELQTQLAILDKAMKGKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVELDLDEAISKHNDIRAHSCPSVWKKTKNSAccession NumberQ28520 PubMed ID7832752 eggNOG DBprNOG18456Ensembl DBENSMMUT00000028601, ENSMMUT00000028602CATHG3DSA:4.10.740.10, G3DSA:2.60.120.200GeneID DB694845GO DB0005576, 0005509, 0007596InterPro DBIPR017857, IPR002383, IPR008985, IPR013320, IPR006209, IPR006210, IPR013032, IPR000152, IPR000742, IPR001881, IPR013091, IPR018097, IPR000294, IPR001791, IPR012679, IPR012680KEGGmcc:694845NCBIL31380, AAA70376OMIM105200, 134820, 202400, 134830, 202400, 134850, 202400, 176930, 601367, 134390, 188055, 227400, 600880, 601367, 612309, 227500, 134500, 306700, 300746, 306900, 227600, 176860, 188050, 612283, 612304, 176880, 612336PfamPF00008, PF07645, PF00594, PF00054, PF02210PROSITE DBPS00010, PS00022, PS01186, PS50026, PS01187, PS00011, PS50998, PS50025SMART DBSM00181, SM00179, SM00069, SM00282UniGeneMmu.3033
Result
Protein S
Function: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. Post-translational modification: The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains (By similarity). Similarity: Contains 4 EGF-like domains. Contains 1 Gla (gamma-carboxy-glutamate) domain. Contains 2 laminin G-like domains. Subcellular location: Secreted. Tissue specificity: Plasma. Sequence length: 649 AA.
SKQQASQVLVRKRRANSMLEETKQGNLERECIEELCNKEEAREVFENDPETDYFYPKYLVCLRSFQSGLFTAARQSTDAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGERCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKSGFVMLSNKKDCKDVDECSLKPNMCGTAVCKNIPGDFECECPEGYRYNLKSKSCEDVDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEAVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSQGVILYAESIDHSAWLLIALRGGKIEVQLKNEHTSKITTGGDIINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAEFHIDYNNGSNAEGWHINVTLNIRPSTGTGVMLALVSSNNTVPFAVSLVDSTSEKSQDIVISVENTVIYRIQALSLCSYQRSHLEFRVNRNNLELLTPLKIETISQEELQTQLAILDKAMKGKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVELDLDEAISKHNDIRAHSCPSVWKKTKNS
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