Result

Untitled Document

  Protein C

SourceCapra hircus (goat)
Taxonomy Capra hircus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra.
KeywordsBlood coagulation; Disulfide bond; Glycoprotein; Hydrolase; Protease; Serine protease.
Details
Function: Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids.

Similarity: Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain.

Tissue specificity: Plasma; synthesized in the liver.

Sequence length: 157 AA.

Sequence
ESWEVDLDIKEVIVRPNYTKSTSDNDIALLHLAKPATLSQTIVPICLPDSGLSERKLTQV
GQETVVTGWGYRDETKKNRTSILNFIKIPVVSYNACVHAMENKVSENMLCAGILGNPRDA
CEGDSGGPMVTFFRGTWFLVGLVSWGEGCGRLNNYGI
Accession NumberQ28315 
PubMed ID8043441 
GO DB0004252, 0007596, 0006508
InterPro DBIPR018114, IPR001254, IPR001314, IPR009003
NCBID43752, BAA07809
OMIM105200, 134820, 202400, 134830, 202400, 134850, 202400, 176930, 601367, 134390, 188055, 227400, 600880, 601367, 612309, 227500, 134500, 306700, 300746, 306900, 227600, 176860, 188050, 612283, 612304
PfamPF00089
PROSITE DBPS50240, PS00134, PS00135
SMART DBSM00020



Useful Links

©Biomedical Informatics Centre, NIRRH, Mumbai