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  Protein C

SourceEquus caballus (horse)
Taxonomy Equus caballus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
KeywordsBlood coagulation; Disulfide bond; Glycoprotein; Hydrolase; Protease; Serine protease.
Details
Function: Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids.

Similarity: Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain.

Tissue specificity: Plasma; synthesized in the liver.

Sequence length: 157 AA.

Sequence
ENGEVDLDIQEVIMHPNYSKSSSDNDIALLRLARPATFSQTIVPICLPDSGLSERELTQA
GQETVVTGWGYRSETKRNRTFVLNFIKVPVVPHSECVRTMHNLVSENMLCAGILGDTRDA
CEGDSGGPMVASFRGTWFLVGLVSWGEGCGRLHNYGV
Accession NumberQ28380 
PubMed ID8043441 
Ensembl DBENSECAT00000017498
GO DB0004252, 0007596, 0006508
InterPro DBIPR018114, IPR001254, IPR001314, IPR009003
NCBID43753, BAA07810
OMIM105200, 134820, 202400, 134830, 202400, 134850, 202400, 176930, 601367, 134390, 188055, 227400, 600880, 601367, 612309, 227500, 134500, 306700, 300746, 306900, 227600, 176860, 188050, 612283, 612304
PfamPF00089
PROSITE DBPS50240, PS00134, PS00135
SMART DBSM00020



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