Result Untitled Document Coagulation factor XIII B chainSourceMus musculus (house mouse) Taxonomy Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.KeywordsBlood coagulation; Disulfide bond; Glycoprotein; Repeat; Signal; Sushi.DetailsFunction: The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. Similarity: Contains 10 Sushi (CCP/SCR) domains. Subunit structure: Tetramer of two A chains and two B chains. Tissue specificity: Predominantly expressed in liver and kidney. Sequence length: 668 AA. SequenceMTLRHLPFILLLILSGELYAEEKQCDFPTVENGRIAQYYYTFKSFYFPMSVDKKLSFFCLAGYATESGKQEEQIRCTAEGWSPNPRCYKKCLKPDLRNGYVSNDKVLYKLQERMSYGCSSGYKTTGGKDEEVVHCLSAGWSSQPSCRKEQETCLAPELEHGNYSTTQRTFKVKDIVAYTCTAGYYTTTGKQTGEAECQANGWSLTPQCNKLMCSSLRLIENGYFHPVKQTYEEGDLVQFFCHENYYLSGSDLIQCYNFGWYPESPICEGRRNRCPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLCENGKWTEPPKCIEEKEKVACEQPPSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRGSSTITCNRGRWTLPPECVENIENCKPPPDIANGVVVDGLLASYTTGSSVEYRCNEYYLLKGSETSRCEQGAWSSPPVCLEPCTIDVDHMNRNNIQLKWKYEGKILHGDLIDFVCKQGYNLSPSIPLSEISAQCNRGDVRYPMCIRKESKGMCASPPVIRNGDIVSSAARTYENGSSVEYRCFDNHFLQGSQNVYCVDGVWTTPPSCLEPCTLSFVEMDKNYLQLKWNFDNRPLILHGEYIEFMCKRDAYISETSIAGSVLRVQCDRGRLKYPKCTPRDRRLSFQEALRTRRQMEKRAccession NumberQ07968 PubMed ID8468048, 16944957, 17330941 CEX DBMM_F13BeggNOG DBroNOG11688Ensembl DBENSMUST00000027615CATHG3DSA:2.10.70.10GermOnline DBENSMUSG00000026368GO DB0007596InterPro DBIPR016060, IPR000436IPI DBIPI00122117NCBID10071, BAA00963OMIM105200, 134820, 202400, 134830, 202400, 134850, 202400, 176930, 601367, 134390, 188055, 227400, 600880, 601367, 612309, 227500, 134500, 306700, 300746, 306900, 227600, 176860, 188050, 612283, 612304, 176880, 612336, 264900, 612416, 234000, 610618, 610619, 229000, 612423, 107300, 188050, 134570, 134580PfamPF00084PROSITE DBPS50923SMART DBSM00032UCSCuc007cwk.1UniGeneMm.30105
Result
Coagulation factor XIII B chain
Function: The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. Similarity: Contains 10 Sushi (CCP/SCR) domains. Subunit structure: Tetramer of two A chains and two B chains. Tissue specificity: Predominantly expressed in liver and kidney. Sequence length: 668 AA.
MTLRHLPFILLLILSGELYAEEKQCDFPTVENGRIAQYYYTFKSFYFPMSVDKKLSFFCLAGYATESGKQEEQIRCTAEGWSPNPRCYKKCLKPDLRNGYVSNDKVLYKLQERMSYGCSSGYKTTGGKDEEVVHCLSAGWSSQPSCRKEQETCLAPELEHGNYSTTQRTFKVKDIVAYTCTAGYYTTTGKQTGEAECQANGWSLTPQCNKLMCSSLRLIENGYFHPVKQTYEEGDLVQFFCHENYYLSGSDLIQCYNFGWYPESPICEGRRNRCPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLCENGKWTEPPKCIEEKEKVACEQPPSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRGSSTITCNRGRWTLPPECVENIENCKPPPDIANGVVVDGLLASYTTGSSVEYRCNEYYLLKGSETSRCEQGAWSSPPVCLEPCTIDVDHMNRNNIQLKWKYEGKILHGDLIDFVCKQGYNLSPSIPLSEISAQCNRGDVRYPMCIRKESKGMCASPPVIRNGDIVSSAARTYENGSSVEYRCFDNHFLQGSQNVYCVDGVWTTPPSCLEPCTLSFVEMDKNYLQLKWNFDNRPLILHGEYIEFMCKRDAYISETSIAGSVLRVQCDRGRLKYPKCTPRDRRLSFQEALRTRRQMEKR
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