Result

  Coagulation factor III

Source	Oncorhynchus mykiss (rainbow trout)
Taxonomy	Oncorhynchus mykiss Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Euteleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus.
Keywords	Signal.
Details Function: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. Similarity: Belongs to the tissue factor family. Contains 2 fibronectin type-III domains. Subcellular location: Membrane; Single-pass type I membrane protein. Tissue specificity: Brain, heart. Sequence length: 294 AA.
Sequence MEDVRTFLHFGVLLSSVLFTIGAAGEDYFPEAMDVQWVSNNFKTILTWGPEPTNYTYTVE FSRVGKDRQRNPHCIRSSRTECDLTNELRNLQETYSADILSEPLPGVTSDLVEFPYTRAE RFSPYKHTKIGGPAFKIVQSEDKTKMTLHIQDPLTPLYKDDQLLTIRDIFKSDLKYRVIY NKAGSTGKKEKMSDLRDVELTNLDKGQSYCVIVAAYIPSRSAQKRLGDWSKAQCSPRENK TIFEEFSFGVISGAIGIMLAIFIILITLTVVCCKRCCCKKTKTVDKDNLQMSPV
Accession Number	Q90W13
PubMed ID	11886173
CATH	G3DSA:2.60.40.30
GO DB	0016021, 0007596
InterPro DB	IPR008957, IPR001187
NCBI	AJ295167.2, CAC82787
OMIM	105200, 134820, 202400, 134830, 202400, 134850, 202400, 176930, 601367, 134390
Pfam	PF01108