Result

  Coagulation factor IX

Source	Danio rerio (zebrafish)
Taxonomy	Danio rerio Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio.
Details Function: Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2 ) ions, phospholipids, and factor VIIIa. Post-translational modification: Activated by factor XIa, which excises the activation peptide. Similarity: Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain. Subcellular location: Secreted. Subunit structure: Heterodimer of a light chain and a heavy chain; disulfide-linked. Tissue specificity: Synthesized primarily in the liver and secreted in plasma. Sequence length: 503 AA.
Sequence MASFILVLFPFLLLQAALGSVFLDGEKADSVLWRRRRANTWLFEEFLPGNVERECIEEKC VLEEAREAFENDEKTMEFWASYVDGNQCKPSPCQNQGTCEDQMGTYSCNCLARFCWQNCE IVTAKKCDVDNGGCEHFCVLLESHKTQCRVHMDTNSQKMDFTCEPIVKFPCGKTSKPAVK TFGTASVTNTTAQSSNKTIKSTSSIPKPDNLTNPTNSKDIKEKLAPPRAKLPKWAFEEYL TSPAPTVSGLKSRIIGGNSALPGEIPWQVALVSRSTQQVFCGGSILNPLWVITAAHCLLG NHNGSFYIRVGEHDVSKIEGTEQNVDVIKLISHPRYNSKVSLFNHDIALLRLRSPIRLTP TVRPICLGPMVFSNTLLQSGTLATVSGWGRVRFQGRSAATLQKIELPYVDRTVCKESSSD PITHFMFCAGHSDSPKDACQGDSGGPHVMRYHNTWFLTGIISWGEECAKKGKYGVYTQVG NYYRWIQHTMGVTTGALLTNVDQ
Accession Number	Q8AYE4
PubMed ID	12482404
Ensembl DB	ENSDARG00000010097
CATH	G3DSA:4.10.740.10
GO DB	0005576, 0005509, 0004252, 0007596, 0006508
InterPro DB	IPR000152, IPR002383, IPR000742, IPR001881, IPR012224, IPR009003, IPR001254, IPR001314, IPR000294
NCBI	AF515270, AAN71001
OMIM	105200, 134820, 202400, 134830, 202400, 134850, 202400, 176930, 601367, 134390, 188055, 227400, 600880, 601367, 612309, 227500, 134500, 306700, 300746, 306900, 227600
Pfam	PF00594, PF00089
PROSITE DB	PS00010, PS50026, PS01187, PS00011, PS50998, PS50240, PS00134, PS00135
SMART DB	SM00179, SM00069, SM00020
UniGene	Dr.20017