Result Untitled Document PlasminogenSourceOncorhynchus mykiss (rainbow trout) Taxonomy Oncorhynchus mykiss Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Euteleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus.KeywordsBlood coagulation; Fibrinolysis; Hydrolase; Kringle; Protease; Repeat; Serine protease; Signal; Tissue remodeling.DetailsFunction: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation; in ovulation it weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. It cleaves fibrin, fibronectin, thrombospondin, laminin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4 (By similarity). Similarity: Belongs to the peptidase S1 family. Sequence length: 814 AA. SequenceMDLYKAVLLGFLFSAVSAGILDEYAKTEGARIMSILKREYSVGTVLECAIKCNAETAFTCRSFIYIEKDQECMTIPANTKTEQVLRRTSTALYEKKVYLMECVNGIGMDYRGTKSKTKSGKKCQRWASKYPHKPNMTPSTHPNADLESDFCRNPDGDSKGPWCYTRDPETRWETCNVQDCSEECTHCNGEDYRGKISTTENGYTCQRWDAQKPHNHGYSPSALPEKYLEEDYCRNPDGDPKPWCFTTSPSKRWDFCSIPRCTSEPPTVVEELTCSTGDGGAYRGTVAVTTSGKACQVWAAQTPQKHNRTPDNYPCKGLDLNYCRNPDNERMPWCYTTDPETRWEYCKVPSCGDVPGPDDAAPTPAEEDCYVGSGSEYRGMVTETISGKKCQSWGSMTPHSHKKTPQDFPKADLRRNLCRNPDGDRAPWCYTTDPSVRWEFCAVEKCPTPPKPTSKPDKPDKPDKPDKPDKPDQPKPTPDQTPSADCKVGNGGTYRGPTSMTMLGVTCQRWSSQSPHQHASFNPESHPDKGLESNNCRNPDNDVNGPWCYTTDRSKKWDYCQIPDCAGLKCGQPVTKPKRCFGRIVGDCVSKPHSWPWQISLRTNTGVHFCGGTLIAPQWVLTAAHCLERSKRPSAYKVFMGTQTERANEVTKQERNLENLILGPDRTDIALLKLETPALINDKVLPACLPEKDYVVPPGTECYVTGWGETQGTGGDGLLKETGFPVIENKVCNRPAYLNNRVKDHEMCAGNIEGGTDSCQGDSGGPLVCHAQNSFVLQGVTSWGLGCANALKPGVYVRVSKFTDWINSQMKMHSAccession NumberQ5DVP8 CATHG3DSA:2.40.20.10GO DB0005509, 0008233, 0004283, 0007596, 0050874, 0006508InterPro DBIPR000001, IPR013806, IPR003014, IPR003609, IPR011358, IPR009003, IPR001254, IPR001314, IPR003966NCBIAJ548828, CAD69012OMIM105200, 134820, 202400, 134830, 202400, 134850, 202400, 176930, 601367, 134390, 188055, 227400, 600880, 601367, 612309, 227500, 134500, 306700, 300746, 306900, 227600, 176860, 188050, 612283, 612304, 176880, 612336, 264900, 612416, 234000, 610618, 610619, 229000, 612423, 107300, 188050, 134570, 134580, 193400, 277480, 228960, 612358, 176895, 173350, 188050, 217090PfamPF00051, PF00024, PF00089PROSITE DBPS00021, PS50070, PS50948, PS50240, PS00134, PS00135SMART DBSM00130, SM00020
Result
Plasminogen
Function: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation; in ovulation it weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. It cleaves fibrin, fibronectin, thrombospondin, laminin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4 (By similarity). Similarity: Belongs to the peptidase S1 family. Sequence length: 814 AA.
MDLYKAVLLGFLFSAVSAGILDEYAKTEGARIMSILKREYSVGTVLECAIKCNAETAFTCRSFIYIEKDQECMTIPANTKTEQVLRRTSTALYEKKVYLMECVNGIGMDYRGTKSKTKSGKKCQRWASKYPHKPNMTPSTHPNADLESDFCRNPDGDSKGPWCYTRDPETRWETCNVQDCSEECTHCNGEDYRGKISTTENGYTCQRWDAQKPHNHGYSPSALPEKYLEEDYCRNPDGDPKPWCFTTSPSKRWDFCSIPRCTSEPPTVVEELTCSTGDGGAYRGTVAVTTSGKACQVWAAQTPQKHNRTPDNYPCKGLDLNYCRNPDNERMPWCYTTDPETRWEYCKVPSCGDVPGPDDAAPTPAEEDCYVGSGSEYRGMVTETISGKKCQSWGSMTPHSHKKTPQDFPKADLRRNLCRNPDGDRAPWCYTTDPSVRWEFCAVEKCPTPPKPTSKPDKPDKPDKPDKPDKPDQPKPTPDQTPSADCKVGNGGTYRGPTSMTMLGVTCQRWSSQSPHQHASFNPESHPDKGLESNNCRNPDNDVNGPWCYTTDRSKKWDYCQIPDCAGLKCGQPVTKPKRCFGRIVGDCVSKPHSWPWQISLRTNTGVHFCGGTLIAPQWVLTAAHCLERSKRPSAYKVFMGTQTERANEVTKQERNLENLILGPDRTDIALLKLETPALINDKVLPACLPEKDYVVPPGTECYVTGWGETQGTGGDGLLKETGFPVIENKVCNRPAYLNNRVKDHEMCAGNIEGGTDSCQGDSGGPLVCHAQNSFVLQGVTSWGLGCANALKPGVYVRVSKFTDWINSQMKMHS
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